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irene.gobe

Picture
Dr Irene Gobe
Title
Dr
Firstname
Irene
Lastname
Gobe
Position
Lecturer
Office
244H/ 125
Phone
4485
Professional Qualifications

1. PhD Medical Microbiology (Molecular Mycobacteriology), UCT, (2016-2021)

2. Msc Medical Microbiology, Surrey (2011-2013)Ìý

3.BHSc (Medical Laboratory Science), UOIT (2006-2009)

Brief Biography

I graduated in 2009 with BHSc (Hons)Ìý with a major inÌýÌýMedical Laboratory Science from the University ofÌý Ontario Institute of Technology ( Canada). Upon completion of my first degree I started my career as research assistant at the Botswana Harvad aids institute partnership, Where I was involved in a study on the prevalence of HIV/AIDS among pregnant women in Botswana.ÌýÌýI then become aÌýÌýMedical Scientific Officer at Bokamoso Private Hospital in Botswana where I was working in a diagnosticÌýÌýlaboratory.ÌýI became interested inÌý tuberculosis while I was working at Bokamoso Private Hospital where I became acutely aware ofÌý the prevalence of tuberculosis in Botswana.I started my MSc studies at the University of Surrey ( UK) in 2011. My MSc research project involved studying the metabolism of M. tuberculosis. During thisÌý research project, I obtained extensive training in applying molecular-biology techniques inÌý studying metabolism of M. tuberculosis. It also gave me an insight into the pathogenesis ofÌý tuberculosis. I wantedÌýto expand my experience by studying this important pathogen at aÌý doctoral level. Therefore I did my PhDÌýstudies at the university of Capetown from 2016-2021.Ìý My PhD research involved studying the intrinsic resistome of mycobacteria with the aim of finding new drug targets that will render the bacteria susceptible to existing drug treatments.ÌýÌý

Teaching Areas

Medical Microbiology

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- Clinical Bacteriology

- Molecular Biology

Ìý

Research Areas

Medical Microbiology related research including

- M. tuberculosis research

- Antimicrobial drug research

- Molecular diagnostics

- bacteriology

-Virology

Postgraduate Supervision Areas

Medical Microbiology related research including

- M. tuberculosis research

- Antimicrobial drug research

- Molecular diagnostics

- bacteriology

-Virology

Selected Publications

1.ÌýBasu, P., Sandhu, N., Bhatt, A., Singh, A., Balhana, R., Gobe, I., ... & Beale, M. H. (2018). The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis.ÌýJournal of Biological Chemistry,Ìý293(15), 5695-5704.

2.ÌýGobe, I., Koto, G. F., Molebatsi, K., Mokomane, M., Kasvosve, I., & Motswaledi, M. S. (2020). Vaccination for some childhood diseases may impact the outcome of covid-19 infections.ÌýmedRxiv.

3.ÌýTimothy, J., Gobe, I., Mhlanga, M. M., & Warner, D. F. (2018). CRISPRi-Seq for the Identification and Characterisation of Essential Mycobacterial Genes and Transcriptional Units.ÌýBioRxiv, 358275.

4.ÌýBasu, P., Sandhu, N., Bhatt, A., Singh, A., Balhana, R., Gobe, I., ... & Beale, M. (2019). When the metabolic model says NO: untangling the Gordian knot of TB’s intracellular metabolism.ÌýAccess Microbiology,Ìý1(1A), 160.

In pursuit of academic excellence